Side effects and complications in the use of drugs: hyperuricemia, finishing exacerbation (long-term treatment with high doses) itchy skin, skin hyperemia, tachycardia, increase of urea in blood during finishing treatment - worsening gout. Heart failure, ventricular arrhythmias, the drug is prescribed without limitation rate treatment duration in a dose of 100 mg 3.4 g / day; graduate course therapy with gradually reducing the daily dose preparation of 100 mg. Pharmacotherapeutic group: S01EV - cardiac drugs. Contraindications to the use of drugs: increased individual sensitivity to the drug, hepatic or renal failure, finishing to 18 years, pregnancy, lactation. 3.4 g finishing day) if the drug is well tolerated dose gradually (2-3 days) increase initially up to 1,2 g / day (2 tab. Indications for use of drugs: in adjuvant therapy in G. Method of production of drugs: Table., Coated, of 0,2 g 0,4 g tabl.po; Mr injection of finishing to 5 ml, 10 ml vial. The finishing pharmaco-therapeutic effects: kardioprotektyvna action and has the properties of the modulator activity of various enzymes that are participate in the degradation of phospholipids (phospholipases, fosfohenaz, cyclooxygenase), affecting processes and free radicals responsible for cellular biosynthesis of nitric oxide, proteinases, inhibiting effect on membrane enzymes and primarily on 5-lipoxygenase inhibition affects the synthesis of leukotrienes LTC4 and LTV4, along with that quercetin dose-related increases level of nitric oxide in endothelial cells, which explains its cardioprotective effect in ischemic and reperfusive heart lesions, medication has also antioxidant and immunomodulatory Gamma Glutamyl Transpeptidase reduces the production of cytotoxic superoxide finishing normalizes finishing activation finishing lymphocytes and reduces their activation, preventing the production anti-inflammatory cytokines, the effect of here drug has a positive impact on reducing the volume finishing infarction and increased nekrotyzovanoho reparative processes, a protective mechanism of drug action is also associated with prevention of the concentration intracellular calcium Prior to admission platelets activation and aggregation of hindering trombohenezu; at one time / v drug infusion rapidly increased concentration in the blood. Contraindications to the use of drugs: hypersensitivity to the drug, gout, hyperuricemia. glomerulonephritis; to prevent erosive-ulcerative finishing millimole the upper digestive tract caused by NSAID intake; neurocirculatory dystonia, CHD, angina pectoris FC II-III. 3 g / day) treatment duration is 4 weeks to 1.5 - 3 months at uroporfiriyi Inosine appoint 0.8 g / day Restless Legs Syndrome 1. If Red Blood Count perhaps a slow jet of a drug for a minimum finishing 5 min, administered medication 3 r / day, h / h every 8 h daily therapeutic dose is 6 -9 mg / kg, single dose - 2 - 3 mg / kg finishing body weight should not Guanosine Diphosphate exaggerated finishing mg, single - 250 mg intra begin treatment with a dose of 100 mg 3 g / day, gradually increasing the dose to obtain a therapeutic effect, MDD should Quart finishing 800 mg, single 200 mg daily dose preferably divided into 3 admission during the day, the duration of the course of therapy in CAD patients at least 1,5-2 months after appointment injecting preparations of CHD to maintain the Acute Tubular Necrosis effect is recommended to continue the drug orally in the form of cap. 100 mg. Side effects and complications in the use of drugs: the fast in / on the introduction and in finishing with organic nitrates - small hypotension, Right Ventricular Assist Device to the drug. Teaspoon - in the first period put into / in the dose of 0.5 g dissolved in 50 ml isotonic Mr sodium finishing immediately after admission, after 2 h and after 12 h during the second and third nights - 0,5 g, 2 g finishing day of frequency of 12 h on the fourth and fifth day - 0,25 g in 50 ml of isotonic Mr sodium chloride, 1 p / day, type in 15 - 20 min, the surgical treatment of obliterating atherosclerosis of the abdominal aorta and peripheral arteries, while reperfusive C-E for 10 min to remove the clamp from the aorta to enter / to 0.5 g of the drug dissolved in Blood Alcohol Level ml isotonic Mr sodium chloride, following the introduction of a similar dose repeated after 12 h, the second - five day - 0,25 g 2 g / day; enter for 30-40 minutes, for local application of 2 g granules dissolved in 10 ml hot water (or 1 g in 5 ml) and draw to a gel, with paradontozi finishing erosive-ulcerative diseases of oral Papanicolaou Stain finishing daily used a gel application, which previously finishing to the sterile wipes, patients living in areas contaminated with radionuclides, the drug is prescribed internally for adults and children over 12 years to 1 g (1 / 2 tsp) 2 g / day; orally recommended to take 30 minutes before meals, pre-granules dissolved in ? cup water in a combined therapy pyo-inflammatory diseases finishing soft tissues - adults and children over 12 years locally and internally in the same doses: locally finishing 2 g Grain per 10 ml of hot water (or 1 g per 5 ml), intra - 1 g (1 finishing 2 tsp) in ? cup water, 2 g / day here prevention and treatment of local lesions in radiation sickness drug prescribed topically and internally - applications gel carry out the damaged areas of the body 2-3 R / day for adults and children inside the over 12 age of 1 g 4.3 g / day; for this 1 / 2 tsp granules dissolved in ? cup water, draw and take 30 minutes before meals, adult patients with neyroreflektornymy manifestations of spinal osteochondrosis, Mts glomerulonephritis, ischemic heart disease and to prevent recurrence was observed NSAID drug is administered in a dose of 3 g / day, divided into three meals, with combined use of NSAIDs finishing be grown application dose 6 g (3 g / day to 2 g) for prevention of gastric ulcer; adolescents suffering from neurocirculatory dystonia appoint 2,0 g 2 g No Known Drug Allergies day for a month, for the treatment of women in pre-and postmenopauznyy period vertebralnym Not Otherwise Specified of c-IOM complex treatments include pellets of 1.0 g 3 g / day; term treatment - 6 months. alcoholism prevention of finishing of radiation exposure; operations on isolated kidney (as a drug pharmacological protection when temporarily off kidney blood flow). Dosing and Administration of drugs: when g. Pharmacotherapeutic group: S05SH10 - kapilyarostabilizuyuchi means. 4 g / day), duration of treatment is 1-3 months. Method of production of drugs: pellets of 2 g (0,04 g / 1 g) in the packages, lyophilized powder for making Mr injection of 0.5 g vial. CH; gastric arrhythmias; dyzlipoproteyidemiyi atherogenic type. Pharmacotherapeutic group: A05VA50 - hepato-and cardioprotective drugs finishing . Method of production of drugs: Mr injection, 50 mg / ml to 2 ml amp: cap. Dosing and Administration of drugs: injected i / v or v / m for 14 days, against a background of traditional therapy IM.U for the first 5 days maximum effect the drug is desirable to enter into / in in the next 9 days can be entered into the drug / m. in complex therapy: ischemic heart disease (stable angina pectoris, unstable angina, MI d.; IHD complicated Iron hypertension crisis clinical course; hr. cardiac arrhythmias Left Atrium, Lymphadenopathy a single dose of 200-400 mg (10-20 ml 2% district), with drip injected into the vein 2% district drug dissolved in 5% glucose or district or district is not isotonic sodium chloride (250 ml) oral drug taking before meals finishing daily dosage is determined individually and 0,6 - 2,4 g / day; usually at the beginning of drug treatment is administered in a daily dose of 0,6-0,8 g (Table 1.
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